Our Precision Medicine Pipelines

Housed at WIMR within Westmead Research Hub, we have the end-to-end facilitaties to provide for your precision medicine needs. The latest cutting-edge technologies, supported by MRFF Grants, mean that whether you would like to hand your samples to us and then receive insights from your data, or whether you’d prefer to be involved in any or all of the steps along the way, we’re here to support you in bringing precision medicine to clinical care. To achieve this, our researchers follow a structured approach that involves two key pipelines:

  • Discovery pipelines, where new biomarkers are identified, and

  • Screening pipelines, where these biomarkers are tested and validated in patient samples.

What sets us apart

Precision medicine research often requires navigating multiple facilities, providers, and systems, a process that can be complex, slow, and fragmented. PrecisionGO changes this by integrating all the capabilities you need into one platform, coordinated through a single point of contact.

This means:

  • Faster project setup and execution

  • Consistent quality and governance from start to finish

  • A clear line of sight from initial concept to clinical translation

PrecisionGO is open access, available to all researchers and clinicians, regardless of institutional affiliation, across Australia and internationally. We bring together nine advanced core facilities (Histology, Genomics, Proteomics, Cytometry, Bioresources, Preclinical Imaging, Imaging, Biobanking, Bioinformatics) under one platform.

The PrecisionGO Digital Platform adds significant value to the work of the program, connecting data from the research pathway through a secure interface. It integration of multi-omics data from our core facilities with hospital systems, supporting projects to have a clearer line of sight towards clinical translation.

What we offer

Tissue profiling to assess cellular distributions, study cell interactions and characterise cell-type specific gene signatures within intact tissue:

  • Single cell and subcellular resolution tissue mapping

  • Comprehensive whole transcriptome profiling of tissue sections

  • Targeted gene expression analysis with pre-designed or custom gene panels

Cellular profiling to functionally characterise and classify cell types based on whole transcriptome and protein data

  • Single cell RNA sequencing

  • Single cell multiomics for gene expression and protein profiling

  • Immune receptor diversity profiling (TCR/BCR sequencing)

Genomic profiling for identifying pathogenic genomic variants in DNA and gene expression signatures from RNA

  • Whole genome sequencing

  • Targeted and custom panel sequencing

  • Bulk RNA sequencing